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Medchemexpress LLC GW806742X hydrochloride | 98.3% | 610.01 | 5 MG

Supplier: Medchemexpress LLC 5MGHY112292A
GW806742X hydrochloride is an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain-Like protein) inhibitor. It binds the MLKL pseudokinase domain with a Kd of 9.3 μM and exhibits activity against VEGFR2 with an IC50 of 2 nM. This compound retards MLKL membrane translocation and inhibits necroptosis. This product is for research use only.
- Potent MLKL inhibitor
- Activity against VEGFR2 (IC50=2 nM)
- Retards MLKL membrane translocation
- Inhibits necroptosis
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