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Apexbio Technology LLC GYKI 47261 dihydrochloride 220445-20-5 50mg
SDP

Catalog No. 5000088997
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GYKI 47261 dihydrochloride is a non-competitive antagonist of AMPA receptors a class of ionotropic glutamate receptors mediating excitatory neurotransmission By blocking AMPA-induced currents in a concentration-dependent manner it regulates glutamatergic signaling In research it has been used to evaluate neuroprotection in ischemic models study motor dysfunction and dyskinesias from dopaminergic therapy assess tremor suppression and probe AMPA receptor roles in neurological disorders Additionally it modulates CYP2E1 enzyme activity in human and rodent hepatocytes These properties support its application in studies of neuroprotection movement disorders tremor regulation neurological pathology and metabolism

Catalog No. 50-000-88997 Supplier Apexbio Technology LLC Supplier No. B727450
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GYKI 47261 dihydrochloride is a non-competitive antagonist of AMPA receptors a class of ionotropic glutamate receptors mediating excitatory neurotransmission By blocking AMPA-induced currents in a concentration-dependent manner it regulates glutamatergic signaling In research it has been used to evaluate neuroprotection in ischemic models study motor dysfunction and dyskinesias from dopaminergic therapy assess tremor suppression and probe AMPA receptor roles in neurological disorders Additionally it modulates CYP2E1 enzyme activity in human and rodent hepatocytes These properties support its application in studies of neuroprotection movement disorders tremor regulation neurological pathology and metabolism

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