Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Gypenoside XLIX | 94987-08-3 | 1047.23 | 5 MG
Supplier: Medchemexpress LLC HYN19905MG
Gypenoside XLIX, isolated from Gynostemma pentaphyllum, is a multifunctional bioactive compound. It acts as a PPAR-α agonist and binds to SIRT1, inhibiting TLR4-mediated NF-κB signaling and reducing ROS accumulation.
- Targets SIRT1 to block YAP-NLRP3 activation, improving sepsis-induced cardiomyopathy.
- Inhibits apoptosis, pyroptosis, autophagy, and lipid peroxidation.
- Alleviates sepsis-induced splenic injury, inflammation, and oxidative stress.
- Mitigates sepsis-associated encephalopathy by targeting PPAR-α.
- Prevents acute kidney injury by inhibiting IGFBP7/IGF1R-mediated programmed cell death.
- Inhibits vascular cell adhesion molecule-1 expression in human endothelial cells.
- Used in research for acute liver/lung injury, cardiomyopathy, and acute kidney injury.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?