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Medchemexpress LLC Gypenoside XLIX | 94987-08-3 | 1047.23 | 5 MG
SDP

Catalog No. 5000414974
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Gypenoside XLIX, isolated from Gynostemma pentaphyllum, is a multifunctional bioactive compound. It acts as a PPAR-α agonist and binds to SIRT1, inhibiting TLR4-mediated NF-κB signaling and reducing ROS accumulation.

  • Targets SIRT1 to block YAP-NLRP3 activation, improving sepsis-induced cardiomyopathy.
  • Inhibits apoptosis, pyroptosis, autophagy, and lipid peroxidation.
  • Alleviates sepsis-induced splenic injury, inflammation, and oxidative stress.
  • Mitigates sepsis-associated encephalopathy by targeting PPAR-α.
  • Prevents acute kidney injury by inhibiting IGFBP7/IGF1R-mediated programmed cell death.
  • Inhibits vascular cell adhesion molecule-1 expression in human endothelial cells.
  • Used in research for acute liver/lung injury, cardiomyopathy, and acute kidney injury.

Catalog No. 50-004-14974 Supplier Medchemexpress LLC Supplier No. HYN19905MG
May include imposed supplier surcharges.
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Gypenoside XLIX, isolated from Gynostemma pentaphyllum, is a multifunctional bioactive compound. It acts as a PPAR-α agonist and binds to SIRT1, inhibiting TLR4-mediated NF-κB signaling and reducing ROS accumulation.

  • Targets SIRT1 to block YAP-NLRP3 activation, improving sepsis-induced cardiomyopathy.
  • Inhibits apoptosis, pyroptosis, autophagy, and lipid peroxidation.
  • Alleviates sepsis-induced splenic injury, inflammation, and oxidative stress.
  • Mitigates sepsis-associated encephalopathy by targeting PPAR-α.
  • Prevents acute kidney injury by inhibiting IGFBP7/IGF1R-mediated programmed cell death.
  • Inhibits vascular cell adhesion molecule-1 expression in human endothelial cells.
  • Used in research for acute liver/lung injury, cardiomyopathy, and acute kidney injury.

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