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Cayman Chemical GypenosIde XVII 5mg
Supplier: Cayman Chemical 345145 MG
An ANO1 channel activator increases chloride currents in FRT cells expressing human ANO1 (EC50 3 UM) selective for ANO1 over CFTR and ENaCs in FRT cells at 10 UM increases the rate of submucosal gland fluid secretion in human bronchi isolated from patients with cystic fibrosis and healthy individuals at 20 UM increases production of mitochondrial ROS reduces the mitochondrial membrane potential and induces apoptosis in RLMVECs reduces total cell counts in pulmonary artery endothelial cell populations isolated from patients with IPAH activates TRPV1 in HEK293T cells expressing the mouse receptor (EC50 11.6 UM) induces scratching and licking behaviors in wild-type but not Trpv1-/- mice
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