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EPICYPHER INC H3K4me3 Antibody, SNAP-Certified™ for CUT&RUN and CUT&Tag, 100 µg
Supplier: EPICYPHER INC 130060
This H3K4me3 (histone H3 trimethylated at lysine 4) antibody meets EpiCypher’s lot-specific SNAP-Certified™ criteria for specificity and efficient target enrichment in both CUT&RUN and CUT&Tag applications. This requires <20% cross-reactivity to related histone PTMs determined using the SNAP-CUTANA™ K-MetStat Panel of spike-in controls (EpiCypher 19-1002, Figures 1 and 5). High target efficiency is confirmed by consistent genomic enrichment at varying cell inputs: 500k and 50k cells in CUT&RUN (Figures 2-3); 100k and 10k cells in CUT&Tag (Figures 6-7). High efficiency antibodies display similar peak structures (Figures 3 and 7) and highly conserved genome-wide signal (Figures 2 and 6) even at reduced cell numbers. This antibody targets histone H3K4me3, which is enriched at active promoters near transcription start sites (TSS) and promotes gene activation.
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