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Enzo Life Sciences HA-1077 (10mg). CAS: 103745-39-7

Supplier: Enzo Life Sciences BMLEI2330010

Inhibits Rho kinase (ROCK; Ki=0.33μM). Selective protein kinase A and G inhibitor (both Ki’s = 1.6μM). Inhibits agonist-induced activation of NADPH oxidase in human neutrophils (IC50=15μM). Inhibitor of myosin light chain kinase and Ca2+/calmodulin-dependent protein kinase II. Inhibits translocation of PKCβI, PKCβII and PKCζ. Cell permeable Ca2+ antagonist with antivasospastic properties. Alternative name: 1-(5-Isoquinolinesulfonyl)homopiperazine . 2HCl, Fasudil. Purity: ≥98% (TLC). Solubility: Soluble in water (>20mg/ml), methanol or DMSO. Long Term Storage: -20°C.
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