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Medchemexpress LLC Halofantrine hydrochloride | 36167-63-2 | 99.9% | C26H31Cl3F3NO | 5 MG
Supplier: Medchemexpress LLC HYA0148A5MG
Halofantrine hydrochloride is a blocker that delays the delayed rectifier potassium current by inhibiting human ERG channels and is a potent antimalarial agent. It inhibits the Cap1-dependent oxidative stress response of Candida albicans, suppresses ROS responses, and enhances the antifungal activity of oxidative damage agents. Halofantrine hydrochloride exhibits antifungal activity in the Galleria mellonella model and shows antimalarial activity against Plasmodium strains both in vitro and in animal models. It can be used in studies related to invasive candidiasis, falciparum malaria, and vivax malaria.
- Exhibits antifungal activity in the Galleria mellonella model.
- Shows antimalarial activity against Plasmodium strains in vitro and in animal models.
- Can be used in studies related to invasive candidiasis, falciparum malaria, and vivax malaria.
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