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Medchemexpress LLC Halofuginone hydrobromide | 64924-67-0 | 495.59 | 100 MG
Supplier: Medchemexpress LLC HYN1584A100MG
Halofuginone hydrobromide (RU-19110 hydrobromide) is a competitive prolyl-tRNA synthetase inhibitor. This Febrifugine derivative acts as a specific inhibitor of type-I collagen synthesis and helps in attenuating osteoarthritis by inhibiting TGF-β activity. It also functions as a potent pulmonary vasodilator through the activation of Kv channels and blocking voltage-gated, receptor-operated, and store-operated Ca2+ channels.
- Acts as a competitive prolyl-tRNA synthetase inhibitor.
- Inhibits type-I collagen synthesis.
- Attenuates osteoarthritis by inhibiting TGF-β activity.
- Functions as a potent pulmonary vasodilator.
- Activates Kv channels.
- Blocks voltage-gated, receptor-operated, and store-operated Ca2+ channels.
- Possesses anti-malaria effects.
- Demonstrates anti-inflammatory properties.
- Exhibits anti-cancer and anti-fibrosis effects.
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