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Medchemexpress LLC Halofuginone (hydrobromide) | 64924-67-0 | 495.59 | 25 MG
Supplier: Medchemexpress LLC 25MGHYN1584A
Halofuginone hydrobromide, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor. It specifically inhibits type-I collagen synthesis and helps reduce osteoarthritis by inhibiting TGF-β activity. It also acts as a potent pulmonary vasodilator by activating Kv channels and blocking various Ca2+ channels. This compound exhibits a range of beneficial effects.
- Competitively inhibits prolyl-tRNA synthetase
- Inhibits type-I collagen synthesis
- Attenuates osteoarthritis by inhibiting TGF-β activity
- Potent pulmonary vasodilator
- Activates Kv channels and blocks Ca2+ channels
- Exhibits anti-malaria effects
- Provides anti-inflammatory effects
- Shows anti-cancer activity
- Offers anti-fibrosis effects
- Decreases NRF2 protein levels in tumors
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