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Medchemexpress LLC Halofuginone hydrobromide | 64924-67-0 | 495.59 | 5 MG
SDP

Catalog No. 5000415329
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Halofuginone hydrobromide is an analytical standard of Halofuginone (hydrobromide) for research and analytical applications. This Febrifugine derivative is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. It specifically inhibits type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibiting TGF-β activity. Furthermore, it acts as a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated, and store-operated Ca2+ channels.

  • Competitive prolyl-tRNA synthetase inhibitor
  • Specific inhibitor of type-I collagen synthesis
  • Attenuates osteoarthritis by inhibiting TGF-β activity
  • Functions as a potent pulmonary vasodilator
  • Possesses anti-malaria effects
  • Exhibits anti-inflammatory effects
  • Demonstrates anti-cancer effects
  • Shows anti-fibrosis effects

Catalog No. 50-004-15329 Supplier Medchemexpress LLC Supplier No. HYN1584AR5MG
May include imposed supplier surcharges.
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Halofuginone hydrobromide is an analytical standard of Halofuginone (hydrobromide) for research and analytical applications. This Febrifugine derivative is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. It specifically inhibits type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibiting TGF-β activity. Furthermore, it acts as a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated, and store-operated Ca2+ channels.

  • Competitive prolyl-tRNA synthetase inhibitor
  • Specific inhibitor of type-I collagen synthesis
  • Attenuates osteoarthritis by inhibiting TGF-β activity
  • Functions as a potent pulmonary vasodilator
  • Possesses anti-malaria effects
  • Exhibits anti-inflammatory effects
  • Demonstrates anti-cancer effects
  • Shows anti-fibrosis effects

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