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Medchemexpress LLC Halofuginone hydrobromide | 64924-67-0 | 495.59 | 5 MG
Supplier: Medchemexpress LLC HYN1584AR5MG
Halofuginone hydrobromide is an analytical standard of Halofuginone (hydrobromide) for research and analytical applications. This Febrifugine derivative is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. It specifically inhibits type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibiting TGF-β activity. Furthermore, it acts as a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated, and store-operated Ca2+ channels.
- Competitive prolyl-tRNA synthetase inhibitor
- Specific inhibitor of type-I collagen synthesis
- Attenuates osteoarthritis by inhibiting TGF-β activity
- Functions as a potent pulmonary vasodilator
- Possesses anti-malaria effects
- Exhibits anti-inflammatory effects
- Demonstrates anti-cancer effects
- Shows anti-fibrosis effects
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