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Selleck Chemical LLC Harmine hydrochloride S3817-10mM/1mL
Supplier: Selleck Chemical LLC S381710MM/1ML
Harmine (Telepathine) a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A with about 60-fold higher IC50 value for DYRK2 Harmine also inhibits monoamine oxidases (MAOs) PPAR and cdc-like kinases (CLKs) Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM
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