Thermo Scientific™ Harvest RC Centrate Chromatographic Clarifier

Catalog No.	Volume (Metric)
02-558-047	3.8 L
02-557-975	29.2 mL
02-557-744	740 mL
02-557-926	6.0 mL
02-558-010	27.5 mL
02-558-013	1.60 L
02-558-037	640 mL
02-557-863	16.2 L

Catalog No. 02-558-047 Supplier Thermo Scientific™ Supplier No. EMP710RCC020R

Description

Designed to clarify CHO cell culture centrates from conventional or single‐use centrifuges. Available in a range of scaleable single use capsules enabling >95% product recovery and significantly reduced impurities.

• Synthetic fibrous AEX Q-functional chromatography media combined with a 0.2 μm Q-functional polyamide membrane enables single-stage clarification of CHO cell culture centrates.
• Electrostatic separation captures soluble and insoluble impurities, including particles generated by cell shear during centrifugation.
• Effectively removes submicron particles <0.5 μm that can be difficult to capture with traditional depth and membrane filtration.
• Supports mAb product recovery greater than 95%.
• Produces clarified centrate with turbidity <15 NTU and DNA <500 ppb.
• Helps protect downstream sterilizing-grade membrane filters, including 0.1 μm filters.
• Provides predictable scalability from laboratory to manufacturing-scale processes.
• Q-functionalized fibrous media and membrane help reduce particle breakthrough and downstream pressure buildup.

Specifications

• Material (Membrane): Polyamide
• Pore Size: 0.2 μm
• Model: BC2300
• Quantity: 1 Ea.
• Type: Chromatographic Clarifier
• Volume (Metric): 3.8 L
• Length (English): 16 in.
• Height (Metric): 7.6 cm
• Diameter (Metric): 45 cm