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Medchemexpress LLC HDAC6-IN-13 | 2837128-41-1 | C23H22N4O | 50 MG
SDP

Catalog No. 5000375893
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HDAC6-IN-13 (Compound 35m) is a potent, highly selective, orally active HDAC6 inhibitor with an IC50 of 0.019 μM. It also inhibits HDAC1, HDAC2, and HDAC3 with IC50s of 1.53, 2.06, and 1.03 μM, respectively. This compound demonstrates significant BBB permeability and anti-inflammatory activity.

  • Potent and highly selective HDAC6 inhibitor.
  • Exhibits significant blood-brain barrier permeability.
  • Demonstrates anti-inflammatory activity.
  • Slow-on and slow-off tight-binding HDAC6 inhibitor.
  • High oral bioavailability (F% = 93.4%) in mice.
  • Inhibits LPS-induced inflammation in mice.

Catalog No. 50-003-75893 Supplier Medchemexpress LLC Supplier No. HY15126150MG
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HDAC6-IN-13 (Compound 35m) is a potent, highly selective, orally active HDAC6 inhibitor with an IC50 of 0.019 μM. It also inhibits HDAC1, HDAC2, and HDAC3 with IC50s of 1.53, 2.06, and 1.03 μM, respectively. This compound demonstrates significant BBB permeability and anti-inflammatory activity.

  • Potent and highly selective HDAC6 inhibitor.
  • Exhibits significant blood-brain barrier permeability.
  • Demonstrates anti-inflammatory activity.
  • Slow-on and slow-off tight-binding HDAC6 inhibitor.
  • High oral bioavailability (F% = 93.4%) in mice.
  • Inhibits LPS-induced inflammation in mice.

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