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Enzo Life Sciences FLUOR DE LYS HDAC8 fluorometric drug discovery kit (1x96wells)
Supplier: Enzo Life Sciences BMLAK5180001
A FLUOR DE LYS fluorescent assay system. The HDAC8 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human HDAC8 included in the kit. The kit is ideal for chemical library screening for candidate inhibitors or activators or kinetic assay of the enzyme under varying conditions. The FLUOR DE LYS HDAC8 assay is based on the FLUOR DE LYS Substrate and FLUOR DE LYS Developer combination. The assay procedure has two steps. First, the FLUOR DE LYS Substrate, which comprises an acetylated lysine side chain, is incubated with HDAC6. Deacetylation of the substrate sensitizes the substrate so that, in the second step, treatment with the FLUOR DE LYS Developer produces a fluorophore. Alternative name: Histone deacetylase 8 fluorescent assay kit. Applications: Fluorescent detection, HTS Cell-based assays, Activity assay.
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