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Cayman Chemical HDAC8 Substrate 1ea
SDP

Supplier:  Cayman Chemical 7002341 EA

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A PARP1 and PARP2 inhibitor (IC50s 50s 1-14.1 nM) inhibits the proliferation of Capan-1 cells (IC50 0.1 nM) as well as talazoparib- or olaparib-resistant Capan-1 cells (IC50s 1.13 and 0.89 nM respectively) inhibits the proliferation of BRCA1 mutant HCC1937 breast cancer cells (IC50 4.54 nM) reduces tumor growth in an olaparib-resistant MDA-MB-436 breast cancer mouse xenograft model at 12.5 and 25 mg/kg

Catalog No. 50-289-6812


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