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Medchemexpress LLC Heclin | 890605-54-6 | 98.2% | 283.32 | 10 MG

Supplier: Medchemexpress LLC HY11020410MG
Heclin is an inhibitor of HECT E3 ubiquitin ligases, targeting Smurf2, Nedd4, and WWP1 with IC50 values of 6.8, 6.3, and 6.9 μM, respectively. It is utilized in research for gastric cancer.
- Inhibits Smurf2, Nedd4, and WWP1
- Used for gastric cancer research
- Inhibits cell viability and IGF1 signaling in BGC803 and MKN45 cell lines
- Ameliorates epinecidin-1-mediated MyD88 degradation in Raw264.7 cells
- Reduces phosphorylation of Akt
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