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Eurofins Discoverx PathHunter HEK 293 CXCR2 (IL8RB) β-Arrestin Cell Line, 2 vials. (93-0202C1)

Supplier:  Eurofins Discoverx 930202C1

Encompass

The PathHunter CXCR2 (IL8RB) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL8/IL8) based activation of CXCR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CXCR2 and EA-tagged β-Arrestin-2. Activation of CXCR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.

Catalog No. 50-199-9936


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