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Eurofins Discoverx PathHunter HEK 293 IL11R/IL6ST Dimerization Cell Line, 2 vials. (93-1028C1)
Supplier: Eurofins Discoverx 931028C1
The PathHunter IL11R/IL6ST Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. IL-11) induced dimerization of IL11R/IL6ST receptors. This product uses EFC technology. The cell line included overexpresses IL6ST target protein fused to PK alongside IL11R target protein fused to EA. Upon ligand-induced dimerization of IL11R/IL6ST, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/interleukins.
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