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HELIX CHROMATOGRAPHY Amaze RP A1 4.6 x 150 mm, 5 um
Supplier: HELIX CHROMATOGRAPHY AA1461551
Mixed-mode stationary phase combining reversed-phase, cation-exchange, and anion-exclusion mechanisms. Provides broad retention for amino acids, hydrophilic and hydrophobic compounds, inorganic cations, basic drugs, and anionic counter-ions. Offers strong retention for basic analytes under acidic conditions, making it suitable for challenging separations of protonated compounds. Functional groups are integrated on a single ligand. A strong acidic group (pKa ~1) is positioned in the inner layer of the stationary phase close to the silica surface, minimizing interaction with residual silanols and improving peak shape for basic analytes. Incorporates surface-bound ion-pairing functionality, enabling full MS compatibility without the need for mobile phase ion-pairing reagents. Provides comparable selectivity and retention to established mixed-mode stationary phases, enabling direct method transfer with minimal adjustment.
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