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AdipoGen Hellebrin (5 mg)
SDP

Supplier:  AdipoGen AGCN20475M005

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Chemical. CAS: 13289-18-4. Formula: C36H52O15. MW: 724.8. Isolated from Helleborus purpurascens. Highly potent Na+/K+-ATPase inhibitor, blocking the active efflux of Na+ and reuptake of K+. Water soluble cardiotonic glycoside from the class of bufadienolides (with 2-pyrone ring). Inhibits cancer cell growth in vitro. Shown to induce caspase-dependent apoptosis, reducing MDR resistance and the rate of mitochondrial oxidative phosphorylation in cancer cells. Inotropic by increasing the intracellular Ca2+ concentration. Immunosuppressive and anti-inflammatory agent that inhibits allogeneic T cell activation with much higher potency than cortisol or cyclosporin A.

Catalog No. 50-205-3660


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