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Cayman Chemical Hema salcfola Lythrn 25mg
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Supplier:  Cayman Chemical 2580425 MG

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An inhibitor of wild-type and mutant forms of LRRK2 inhibits WT LRRK2 LRRK2G2019S and LRRK2A2016T (IC50s 6.6 2.2 and 47.7 nM respectively) but not LRRK2 containing both mutations (IC50 3080 nM) inhibits phosphorylation of Ser910 and Ser935 of WT LRRK2 and LRRK2G2019S in vitro inhibits Ser935 phosphorylation in vivo in mouse brain spleen and kidney at 30 mg/kg

Catalog No. 50-293-4982


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