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Gibco™ HEP10, Pooled Human Cryopreserved Hepatocytes
Description
CellStream™ Isolation Technology
HEP10™ Pooled Human Hepatocytes are made using our novel patent-pending CellStream Isolation Technology™. This process eliminates the disadvantages of density gradient fractionation prior to cryopreservation of the pool. Instead, we gently isolate and purify the pre-screened, high-viability, and metabolically-active hepatocytes from other cells and debris. The result is a remarkably pure pooled hepatocyte preparation with high viability for use in drug metabolism studies and other biological assays.
10 Donors in One Vial
Each vial of HEP10™ Pooled Human Hepatocytes contains hepatocytes from ten individual donors, 5 female and 5 male donors. Custom HEP10 lots can also be prepared from our broad array of high-quality, single-donor cells. Large lots are also available for extensive studies.
Verified Activity
Each pool is characterized for CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4, CYP3A4⁄5, FMO activity, and NTCP, OATP1B3, and OATP transporter pathways.
Ready for Your Drug Metabolism Experiments
HEP10™ Pooled Human Hepatocytes are useful in a wide variety of applications, including intrinsic clearance, transport, toxicology, biochemistry and cell biology studies.,
Note:
These products require shipment in LN2 vapor dewars therefore additional fees may apply.
Specifications
Specifications
| Cell Passage Number | Passage 0 |
| Content And Storage | Store in a cryostorage dewar or -135°C freezer. |
| Cell Type | Hepatocytes |
| Culture Type | Suspension Cell Culture |
| Form | Cryopreserved |
| Gender | Unisex |
| Species | Human |
| Donor Source | Pooled |
| Format | Tube |
| No. of Cells | 4-8 x 106 |
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Safety and Handling
For Research Use Only. Not for use in diagnostic procedures.
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