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Gibco™ HepaRG™ Cells, Cryopreserved Non-distribution product as customer accommodation. Available on GSA/VA Contract for Federal Government customers only.

HepaRG™ Cells, Cryopreserved

Manufacturer:  Gibco™ HPRGC10

Catalog No. HPRGC10


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Description

Description

The HepaRG™ cell line is an immortalized hepatic cell line that retains many characteristics of primary human hepatocytes. HepaRG™ cells are terminally differentiated and provided in a convenient cryopreserved format. For scientists who need reproducible metabolism data, HepaRG™ cells are an in vitro tool that provides reproducible results in a metabolically complete and scalable system.
  • Obtain biologically relevant results from a metabolically complete system
  • Assess the drug-drug interaction potential of your compound
  • Experience reproducible results from a single population of cells

    Biologically Relevant
    HepaRG™ cells exhibit many characteristics of primary human hepatocytes including morphology, expression of key metabolic enzymes, expression of nuclear receptors, and drug transporters. Unlike HepG2 and Fa2N-4 cells, HepaRG™ cells have high P450 activity and complete expression of all nuclear receptors.

    Predict Metabolism-based Drug-drug Interaction
    HepaRG™ cells respond to prototypical P450 inducers and inhibitors to the same extent as primary hepatocytes, allowing HepaRG™ cells to be used to evaluate potential drug-drug interactions.

    Infinitely Reproducible
    HepaRG™ cells exhibit many characteristics of primary human hepatocytes and are essentially a single donor. These features allow users to obtain physiological relevant results for metabolism-based drug-drug interactions without the concern of donor variability and limited lot sizes that come with relying on donor tissue. (Note: The cells we provide are terminally differentiated).

    HepaRG™ is a trademark of BioPredic International.

    This product(s) resides on a Fisher Scientific GSA or VA contract. If you are viewing this page as a nonregistered user, the price(s) displayed is List Price. To view your GSA or VA contract pricing, log in using your account number, or become a registered user by contacting one of our Customer Service teams. You can also view your contract price by searching for this item(s) on GSA Advantage. To place an order, contact Fisher Scientific Customer Service.

  • Specifications

    Specifications

    Single Donor
    Human
    10 x 106
    Female
    1 vial(s)
    Hepatic Cell
    Cryopreserved
    Adult
    Dry Ice
    HepaRG™
    Hepatocytes
    Safety and Handling

    Safety and Handling

    SDS
    Documents
    Product Certifications
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    For Research Use Only. Not for use in diagnostic procedures.