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Sigma Aldrich Fine Chemicals Biosciences HepaRGTM Cells AHR one

Catalog No. 502907520
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HepaRG is a human hepatoma cell line. The cells possess a pseudodiploid karyotype and have been characterized as an oval ductular bipotent hepatic cell line as they have the ability to differentiate into both biliary and hepatocyte lineages in the presence of DMSO. HepaRG AHR knockout cells express the major xenobiotic sensors (PXR and CAR) drug transporters phase I and II drug metabolizing enzymes as well as key hepatic transcription factors involved in stress response pathways.

Catalog No. 50-290-7520 Supplier Sigma Aldrich Fine Chemicals Biosciences Supplier No. MTOX10131VL
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HepaRG is a human hepatoma cell line. The cells possess a pseudodiploid karyotype and have been characterized as an oval ductular bipotent hepatic cell line as they have the ability to differentiate into both biliary and hepatocyte lineages in the presence of DMSO. HepaRG AHR knockout cells express the major xenobiotic sensors (PXR and CAR) drug transporters phase I and II drug metabolizing enzymes as well as key hepatic transcription factors involved in stress response pathways.

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