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Cayman Chemical HeparIn-bIndng PeptIdetrIf 1mg
SDP

Supplier:  Cayman Chemical 397251 MG

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An inhibitor of ATM kinase (IC50 0.78 nM) selective for ATM over ATR PI3K mTOR and DNA-PK (IC50s 30 12 16 and 29.9 UM respectively) sensitizes glioma cells expressing mutant but not wild-type p53 to ionizing radiation reduces the growth of brain metastases and increases survival in an NCI H2228 mouse xenograft model at 20 mg/kg twice daily p.o. in combination with radiation

Catalog No. 50-291-4754


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