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Cayman Chemical HeTRochromatInProteIn1H100uL
SDP

Catalog No. 502949287
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An Mps1/TTK inhibitor (IC50 0.182 UM) selective for Mps1/TTK over a panel of 59 additional kinases (IC50s 5 UM for all) accelerates mitosis reducing the length of mitosis by approximately 3-fold in U2OS cells induces aneuploidy and apoptosis in A2780 ovarian cancer cells at 1 UM as well as inhibits proliferation in a panel of 127 cancer cell lines (IC50s 0.192-10 UM) reduces tumor growth in an A2780 mouse xenograft model at 90 mg/kg per day

Catalog No. 50-294-9287 Supplier Cayman Chemical Supplier No. 32918100 UL
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An Mps1/TTK inhibitor (IC50 0.182 UM) selective for Mps1/TTK over a panel of 59 additional kinases (IC50s 5 UM for all) accelerates mitosis reducing the length of mitosis by approximately 3-fold in U2OS cells induces aneuploidy and apoptosis in A2780 ovarian cancer cells at 1 UM as well as inhibits proliferation in a panel of 127 cancer cell lines (IC50s 0.192-10 UM) reduces tumor growth in an A2780 mouse xenograft model at 90 mg/kg per day

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