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Cayman Chemical Hexa LIpId 114 10mg

Supplier: Cayman Chemical 4173510 MG

An ionizable cationic lipid (pKa ~6.1) LNPs containing LP-01 and encapsulating both Cas9 mRNA and modified sgRNA for Ttr induce gene editing in liver cells in mice in a dose-dependent manner resulting in reduced serum Ttr levels for at least 12 months subretinal administration of LNPs containing LP-01 and encapsulating both Cas9 mRNA and sgRNA targeting the loxP stop codon induce retinal gene editing in Ai9 mice
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