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BioVendor, LLC Growth Hormone human (hGH) Sensitive ELISA, 96 wells
Supplier: BioVendor, LLC E022
Growth Hormone human (hGH) Sensitive ELISA, 96 wells. High sensitivity (0.0115 ug/L) immunoassay kit for hGH quantification in serum/plasma samples. QC serum included. CALIBRATION RANGE: 0.0115-26 ng/ml. SUMMARY: hGH (somatropin) is the product of GH-1 gene and expressed in pituitary cells. 80% of the gene expression results in a non-glycolsylated 22 kDa protein with 191 amino acids. Excessive hGH secretion, mostly caused by pituitary adenoma, results in childhood in gigantism, in adulthood in acromegaly, leading to enlarged extremities, diabetes, heart insufficiency and tumor growth. Surgical excision of the adenoma is the therapy of choice. If tumor excision is not possible or incomplete, a medicinal therapy with somatostatin preparation is used to inhibit hGH production. Alternatively hGH analoga (e.g. Pegvisomat) are used to block the hGH receptor and inhibit endogenous hGH. hGH determination has been used in diagnostics and therapy control for GH deficiency or GH excess.
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