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Medchemexpress LLC Hh-Ag1.5 (SAg1.5) | 612542-14-0 | ≥98.0% | 526.04 | C28H26ClF2N3OS | 10MG
Supplier: Medchemexpress LLC HY12489910MG
Hh-Ag1.5 is a small-molecule agonist of the Hedgehog signaling pathway that activates Smoothened (Smo) and induces Gli-dependent transcription. It is used in vitro to stimulate Hh signaling, with reported activity at subnanomolar concentrations and documented application in reprogramming and expansion of quiescent liver stem cells.
- Potent Hedgehog pathway agonist with EC50 ≈ 1 nM.
- Selective Smoothened (Smo) receptor agonist with Ki ≈ 0.52 nM.
- Facilitates expansion of quiescent liver stem cells in vitro at 5 μM.
- High purity suitable for cellular assays (≥98% by HPLC).
- Molecular weight 526.04; formula C28H26ClF2N3OS; soluble in DMSO.
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