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Diagnostic Biosystems HHV8 HHV8
Supplier: Diagnostic Biosystems PDM395
HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of nonHodgkin lymphoma affecting the body cavities), and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposi’s sarcoma.
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