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Cayman Chemical HIF-1 (C-Term) Polyclonal Antibody, 1 ea
Supplier: Cayman Chemical 100064211500
Antigen: peptide from the C-terminal region of human HIF-16 Host: rabbit Species Reactivity: (+) human, mouse, and simian HIF-1 Applications: IHC, WB HIF-1 is a transcription factor that accumulates under low-oxygen conditions. Following hypoxic stimulus and cytoplasmic accumulation, HIF-1 migrates to the nucleus where, with other transcription factors, it drives the production of stress-adaptive proteins. This response is essential for maintenance of normal oxidative physiology, however overexpression in cancer cells promotes tumor survival.
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