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Medchemexpress LLC Histamine phosphate | 51-74-1 | 99.3% | C5H15N3O8P2 | 1 ML
Supplier: Medchemexpress LLC HYA012910MM/1ML
Histamine phosphate is a histamine receptor agonist and vasodilator, playing roles in local immune responses, intestinal function, and neurotransmission. It demonstrates antitumor, antioxidant, and anti-inflammatory activities, making it valuable in research for various conditions.
- Exhibits bidirectional regulatory effects on MDA-MB-231 cell proliferation.
- Induces cell cycle arrest at G2/M phase, differentiation, and apoptosis in MDA-MB-231 cells.
- Increases ROS generation and promotes radiosensitivity in MDA-MB-231 cells.
- Inhibits microglia migration and IL-1β release in LPS-stimulated N9 microglial cells.
- Demonstrates analgesic effects at high doses and causes hyperalgesia at low doses in mouse models.
- Can be used in animal modeling to create gastrointestinal ulcer models.
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