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Medchemexpress LLC Histamine phosphate | 51-74-1 | 99.3% | C5H15N3O8P2 | 5 G
Supplier: Medchemexpress LLC HYA01295G
Histamine phosphate, also known as Histamine diphosphate, is a potent agonist for the histamine receptor and functions as a vasodilator. This organic nitrogen compound plays a crucial role in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. It affects the p38 MAPK/Akt signaling pathway and exhibits various biological activities including antitumor, antioxidant, and anti-inflammatory properties, making it valuable in research for conditions like acute myeloid leukemia, malignant melanoma, and renal cell carcinoma.
- Regulates MDA-MB-231 cell proliferation, inducing cell cycle arrest, lipid droplet formation, differentiation, and apoptosis.
- Increases reactive oxygen species (ROS) generation and enhances radiosensitivity in MDA-MB-231 cells.
- Inhibits microglia migration and IL-1β release in LPS-stimulated N9 cells, demonstrating anti-inflammatory effects.
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