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Sigma Aldrich Fine Chemicals Biosciences HiTrapR MabSelectTM PrismA
Supplier: Sigma Aldrich Fine Chemicals Biosciences GE17549854
These HiTrap columns are prepacked with MabSelect PrismA protein A chromatography resin. This affinity resin in the packed column has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein ligand allowing efficient cleaning between monoclonal antibody purification runs. This allows future demands in monoclonal antibody purification to be met including processing of many bispecific antibodies..nbspEnhanced dynamic binding capacity compared with other protein A resins..nbspExcellent alkaline stability enables efficient cleaning and sanitization using 0.5-1.0 M NaOH..nbspConvenient HiTrap format for easy connection to a syringe peristaltic pump or chromatography systems such as an ÄKTA system for convenient process optimization.The enhanced alkaline stability of MabSelect PrismA also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bi
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