Invitrogen™ HIV1 gp120 Synthetic Peptide

Catalog No.	Quantity
PEP0608	50 μg

Catalog No. PEP0608 Supplier Invitrogen™ Supplier No. PEP0608

Description

Synthetic Peptide

This peptide corresponds to 16 amino acids near the amino terminus of HIV-1 gp120. PEP-0608 can be used as a blocking peptide with polyclonal antibody PA5-20488.

Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

Specifications

• Species: Virus
• Purification Method: purified
• Common Name: HIV1 gp120
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: HIV Glycoprotein 120; HIV-1 Glycoprotein 120; Human immunodeficiency virus
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS