The Immudex MHC Dextramer reagent is specifically designed for the precise detection of antigen-specific T cells through flow cytometry. This reagent features a dextran polymer backbone adorned with HLA-A*02:01-peptide complexes, particularly the SLLMWITQC peptide, conjugated with the PE fluorochrome for enhanced visualization. It is intended solely for research applications, providing high avidity binding to identify low-affinity T-cell populations effectively.
- High avidity binding enhances detection of low-affinity T cells and reduces background staining.
- Sensitive detection enables flow cytometric identification of rare CD4+ and CD8+ T cell populations.
- Suitable for diverse research fields, including immune-oncology and autoimmunity.
- Exclusively for research use, not for diagnostic or therapeutic applications.
- Manufactured under cGMP standards for consistency and reliability.