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Medchemexpress LLC Hlcl-61 hydrochloride | 1158279-20-9 | 99.9% | 380.91 | C23H25ClN2O | 5 MG
Supplier: Medchemexpress LLC HY100025A5MG
HLCL-61 hydrochloride is a first-in-class small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) used for research to probe PRMT5-mediated methylation and cellular responses. It reduces cell growth in a dose-dependent manner across multiple leukemia cell lines and inhibits symmetric arginine dimethylation of histones H3 and H4, supporting studies of epigenetic regulation and oncology research.
- Targets PRMT5 to inhibit arginine methylation.
- Reduces cell proliferation in leukemia cell lines; IC50s reported by manufacturer.
- High purity suitable for research applications.
- Soluble in DMSO (50 mg/mL); insoluble in water.
- Solid, white to off-white appearance; store sealed away from moisture under recommended conditions.
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