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Selleck Chemical LLC HLM006474 S8963-100MG
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Catalog No. 5000024070
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HLM006474 is a small molecule pan-E2F inhibitor that inhibits DNA binding to E2F4 with IC50 of 29 8 M in A375 cells HLM006474 induces a reduction in cell proliferation and an increase in apoptosis The CDK/Rb/E2F pathway is commonly disrupted in lung cancer and HLM006474 is shown to have efficacy in lung cancer

Catalog No. 50-000-24070 Supplier Selleck Chemical LLC Supplier No. S8963100MG
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HLM006474 is a small molecule pan-E2F inhibitor that inhibits DNA binding to E2F4 with IC50 of 29 8 M in A375 cells HLM006474 induces a reduction in cell proliferation and an increase in apoptosis The CDK/Rb/E2F pathway is commonly disrupted in lung cancer and HLM006474 is shown to have efficacy in lung cancer

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