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Proteintech Group Inc Hmn CCL20/MIP-3 ELISA 96well
Supplier: Proteintech Group Inc KE0014996T
CCL20, also known as MIP-3 alpha, is a chemokine expressed mainly in the lymphatic tissue, lung and liver produced by cells related with inflammation and autoimmune response such as endothelial cells, neutrophils, natural killer (NK), Th17 cells and B cells among others. CCL20 contributes to inflammatory cell recruitment. CCL20 selectively signals through its receptor CCR6. The ligand-receptor pair CCL20/CCR6 is responsible for the chemoattraction of immature dendritic cells, effector/memory T cells and B cells, and also serves a role in the skin and mucosal surfaces under homeostatic and inflammatory conditions, as well as in pathological processes, such as those associated with cancer and rheumatoid arthritis.
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