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Enzo Life Sciences HNMPA-(AM)3 (5mg). CAS: 120944-03-8

Supplier: Enzo Life Sciences BMLEI2480005
HNMPA-(AM)3 is a cell-permeable analog of HNMPA. It inhibits insulin receptor tyrosine kinase activity (IC50=100 µM) and insulin-stimulated glucose oxidation in isolated rat adipocytes (IC50=10 µM). It has no effect on PKA (at concs. up to 1 mM) or PKC (at concs. up to 420 µM). Inhibits both serine and tyrosine autophosphorylation by the human insulin receptor. Does not affect protein kinase C (PKC) or cAMP-dependent protein kinase (PKA). Alternative name: Hydroxy-2-naphthalenylmethylphosphonic acid tri-acetoxymethyl ester. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (>20mg/ml) or 100% ethanol (>20mg/ml). Long Term Storage: -20°C.
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