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Cayman Chemical Hoechst 33342hydrochlorIde 5mL
Supplier: Cayman Chemical 407975 ML
A guanidine-modified biotin derivative and an inhibitor of iNOS and nNOS (Kis 21.8 and 37.5 UM for the mouse and rat enzymes respectively) prevents hypoxia-ischemia-induced decreases in brain phosphocreatine and ATP levels and increases in edema in the parietal cortex and striatum as well as reduces apoptosis in the parietal- and temporal cortex and striatum in piglets at 0.2 mg/kg every four hours increases survival of and decreases electrographic seizures in hypoxia-ischemia-injured piglets at 0.2 and 1 mg/kg every four hours LNPs containing 2-iminobiotin conjugated to poly-L-lysine have been used to improve LNP tumor targeting uptake and retention compared with LNPs containing biotin conjugated to poly-L-lysine in rats
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