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Medchemexpress LLC HOIPIN-1 | 2470242-33-0 | 99.6% | 304.28 | 10 MG

Supplier: Medchemexpress LLC HY12288110MG
HOIPIN-1 (JTP-0819958) is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM. It suppresses LUBAC-mediated NF-κB activation in vitro and is intended for research use only.
- Selectively inhibits LUBAC-mediated ubiquitination
- Suppresses NF-κB activation in vitro
- Exhibits increased inhibitory activity with longer preincubation times
- Inhibits expression of NF-κB target genes
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