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Medchemexpress LLC Homatropine methylbromide | 80-49-9 | 98.0% | 10 MM * 1 ML
SDP

Catalog No. 5000413077
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Homatropine methylbromide is a muscarinic AChR antagonist. It inhibits muscarinic receptors in both endothelial and smooth muscle, with IC50 values of 162.5 nM and 170.3 nM in WKY-E and SHR-E, respectively. It has been shown to prevent lethality in a rat model of acute organophosphate poisoning.

  • Muscarinic AChR antagonist
  • Inhibits endothelial and smooth muscle muscarinic receptors
  • IC50 values of 162.5 nM (WKY-E) and 170.3 nM (SHR-E)
  • Produces a dose ratio of 259 in atrium from guinea-pigs (20 μM)
  • Comparable to atropine in preventing lethality in a rat model of acute organophosphate poisoning (20 mg/kg)
  • Molecular Weight: 370.28
  • Formula: C17H24BrNO3
  • Appearance: Solid, white to off-white

Catalog No. 50-004-13077 Supplier Medchemexpress LLC Supplier No. HYB138810MM/1ML
May include imposed supplier surcharges.
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Homatropine methylbromide is a muscarinic AChR antagonist. It inhibits muscarinic receptors in both endothelial and smooth muscle, with IC50 values of 162.5 nM and 170.3 nM in WKY-E and SHR-E, respectively. It has been shown to prevent lethality in a rat model of acute organophosphate poisoning.

  • Muscarinic AChR antagonist
  • Inhibits endothelial and smooth muscle muscarinic receptors
  • IC50 values of 162.5 nM (WKY-E) and 170.3 nM (SHR-E)
  • Produces a dose ratio of 259 in atrium from guinea-pigs (20 μM)
  • Comparable to atropine in preventing lethality in a rat model of acute organophosphate poisoning (20 mg/kg)
  • Molecular Weight: 370.28
  • Formula: C17H24BrNO3
  • Appearance: Solid, white to off-white

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