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Medchemexpress LLC HPK1-IN-3 | 2739844-34-7 | 98.61% | 490.45 | 100 MG
SDP

Catalog No. 5000350762
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HPK1-IN-3 is a potent and selective ATP-competitive hematopoietic progenitor kinase 1 (HPK1; MAP4K1) inhibitor with an IC50 of 0.25 nM. It has IL-2 cellular potency with an EC50 of 108 nM in human peripheral blood mononuclear cells (PBMCs).

  • Potent and selective ATP-competitive HPK1 (MAP4K1) inhibitor with an IC50 of 0.25 nM.
  • Exhibits IL-2 cellular potency with an EC50 of 108 nM in human peripheral blood mononuclear cells (PBMCs).
  • Can elevate proinflammatory cytokines IL-6 and TNF-α in human monocyte-derived dendritic cells.

Catalog No. 50-003-50762 Supplier Medchemexpress LLC Supplier No. HY138568100MG
May include imposed supplier surcharges.
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HPK1-IN-3 is a potent and selective ATP-competitive hematopoietic progenitor kinase 1 (HPK1; MAP4K1) inhibitor with an IC50 of 0.25 nM. It has IL-2 cellular potency with an EC50 of 108 nM in human peripheral blood mononuclear cells (PBMCs).

  • Potent and selective ATP-competitive HPK1 (MAP4K1) inhibitor with an IC50 of 0.25 nM.
  • Exhibits IL-2 cellular potency with an EC50 of 108 nM in human peripheral blood mononuclear cells (PBMCs).
  • Can elevate proinflammatory cytokines IL-6 and TNF-α in human monocyte-derived dendritic cells.

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