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Medchemexpress LLC HPV16 E7 (86-93) (TFA) | 98.0% | 929.06 | 10 MG
Supplier: Medchemexpress LLC HYP1778A10MG
HPV16 E7 (86-93) TFA is a human leukocyte antigen (HLA)-A2.1 restricted HPV16 E7-derived peptide, immunogenic in cervical carcinomas. It is for research use only. Precursor T cells specific for the peptide are able to differentiate into HPV-specific effector cells. Peptide-loaded autologous dendritic cells can stimulate a specific cytotoxic CD8+ T-cell response.
- Specific T cells are expandable upon in vitro stimulation with peptide-pulsed dendritic cells.
- Response against K562 cells pulsed with the peptide was significantly blocked by anti-HLA class I Ab w6/32.
- Peptide in IVS culture shows specific T cell expansion.
- The peptide can induce cytotoxic T lymphocyte (CTL) responses if loaded on antigen presenting HLA class I molecules.
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