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Medchemexpress LLC HS-243 | 848249-10-5 | 100.0% | 324.33 | C17H16N4O3 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1349115MG

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HS-243 is a potent, selective small-molecule inhibitor of IRAK-4 and IRAK-1 with reported low-nanomolar potency and demonstrated anti-inflammatory and anticancer activity in vitro. It reduces secretion of multiple proinflammatory cytokines and shows antiproliferative effects in selected cell lines.

  • Potent IRAK-4 inhibition (IC50 20 nM) and IRAK-1 inhibition (IC50 24 nM).
  • Minimal TAK1 activity (IC50 0.5 μM).
  • Reduces secretion of multiple proinflammatory cytokines in cellular assays.
  • Exhibits antiproliferative activity in select cancer cell lines in vitro.
  • High purity (99.95%) white to off-white solid.
  • Molecular weight 324.33; formula C17H16N4O3.
  • Stable as powder at -20°C (3 years) and 4°C (2 years); in solution at -80°C (1 year).

Catalog No. 50-002-22416


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