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Cayman Chemical HS-024 (trifluoroacetate salt), Purity: ≥98%, 5 mg
SDP

Catalog No. 502945726
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An MC4R antagonist (Ki = 0.29 nM); selective for MC4R over MC1R, MC3R, and MC5R (Kis = 18.6, 5.45, and 3.29 nM, respectively); inhibits cAMP accumulation induced by α-MSH in COS-1 cells expressing MC1R, MC3R, MC4R, or MC5R at 100 nM; increases food intake in rats at 0.3, 1, or 3 nmol/animal; intrathecal administration inhibits mechanical allodynia at 30 minutes post-injection in a rat model of spinal nerve ligation-induced neuropathic pain at 1.5 nmol/animal; reduces stress-induced reinstatement of nicotine seeking in the foot shock test in rats

Catalog No. 50-294-5726 Supplier Cayman Chemical Supplier No. 415575 MG
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An MC4R antagonist (Ki = 0.29 nM); selective for MC4R over MC1R, MC3R, and MC5R (Kis = 18.6, 5.45, and 3.29 nM, respectively); inhibits cAMP accumulation induced by α-MSH in COS-1 cells expressing MC1R, MC3R, MC4R, or MC5R at 100 nM; increases food intake in rats at 0.3, 1, or 3 nmol/animal; intrathecal administration inhibits mechanical allodynia at 30 minutes post-injection in a rat model of spinal nerve ligation-induced neuropathic pain at 1.5 nmol/animal; reduces stress-induced reinstatement of nicotine seeking in the foot shock test in rats

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