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Medchemexpress LLC HSGN-94 | 2570797-85-0 | 98.8% | 508.51 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY14681110MM/1ML

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HSGN-94 is a potent antimicrobial agent that inhibits lipoteichoic acid (LTA) biosynthesis. It is effective against drug-resistant Gram-positive bacteria, including MRSA and Vancomycin-resistant Enterococci, also inhibiting their biofilm formation. It reduces pro-inflammatory cytokines and shows in vivo efficacy in an MRSA murine wound infection model.

  • Potent antimicrobial agent targeting lipoteichoic acid (LTA) biosynthesis.
  • Effective against drug-resistant Gram-positive bacteria (MIC values: 0.25-2 μg/mL).
  • Inhibits biofilm formation in MRSA and Vancomycin-resistant Enterococci.
  • Reduces pro-inflammatory cytokines.
  • Demonstrates in vivo efficacy in a murine wound infection model.
  • Directly binds to CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase (PgsA).
  • Downregulates PgsA expression in *S. aureus*.
  • Non-toxic to HaCat cells up to 64 μg/mL.

Catalog No. 50-003-62982


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