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Medchemexpress LLC hSMG-1 inhibitor 11e | 1402452-10-1 | 99.9% | 517.60 | C26H27N7O3S | 100MG
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Catalog No. 5000238267
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hSMG-1 inhibitor 11e is a research-grade, potent and selective inhibitor of the human SMG-1 kinase. It exhibits sub-nanomolar potency (hSMG-1 IC50 <0.05 nM) and pronounced selectivity versus related kinases, and is supplied as a solid or as a 10 mM solution in DMSO for biochemical and cellular studies.

  • Potent hSMG-1 inhibition (IC50 <0.05 nM).
  • High selectivity (>900-fold) over mTOR, with reported IC50s for mTOR 45 nM, PI3Kα 61 nM, PI3Kγ 92 nM.
  • Molecular formula C26H27N7O3S; molecular weight 517.60.
  • Purity 99.9% (manufacturer listed 99.94%, rounded to tenths).
  • Available as solid (including 100 mg) and 10 mM solution in DMSO.
  • Suitable for biochemical kinase assays and cellular pathway studies.

Catalog No. 50-002-38267 Supplier Medchemexpress LLC Supplier No. HY124760100MG
May include imposed supplier surcharges.
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hSMG-1 inhibitor 11e is a research-grade, potent and selective inhibitor of the human SMG-1 kinase. It exhibits sub-nanomolar potency (hSMG-1 IC50 <0.05 nM) and pronounced selectivity versus related kinases, and is supplied as a solid or as a 10 mM solution in DMSO for biochemical and cellular studies.

  • Potent hSMG-1 inhibition (IC50 <0.05 nM).
  • High selectivity (>900-fold) over mTOR, with reported IC50s for mTOR 45 nM, PI3Kα 61 nM, PI3Kγ 92 nM.
  • Molecular formula C26H27N7O3S; molecular weight 517.60.
  • Purity 99.9% (manufacturer listed 99.94%, rounded to tenths).
  • Available as solid (including 100 mg) and 10 mM solution in DMSO.
  • Suitable for biochemical kinase assays and cellular pathway studies.

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