Cayman Chemical HTMTmaleate 10mg

Supplier:  Cayman Chemical 2901810 MG

A histamine H1 receptor agonist; binds to the histamine H4 receptor (Ki = 1.2 µM) but does not increase calcium mobilization in HEK293 cells expressing the receptor at 10 µM; increases intracellular calcium and inositol phosphate levels (EC50s = 19 and 30 µM, respectively) in human peripheral blood lymphocytes; increases proliferation of immortalized mouse small, but not large, cholangiocytes, at 10 µM; increases levels of sheep red blood cell-induced IgG and IgM antibodies in rabbit serum at 10 UG/kg twice per day; induces scratching in mice at an intradermal dose of 0.2 µmol, an effect that is reduced by the H1 receptor antagonist terfenadine

Catalog No. 50-294-1041